Isoniazid-resistant tuberculous spondylodiscitis associated with scrofuloderma
Rev. patol. trop
;
47(4): 247-253, dez. 2018. ilus
Article
in English
| LILACS
| ID: biblio-996645
ABSTRACT
The extrapulmonary forms of tuberculosis are responsible for about 20% of cases. Scrofuloderma is the cutaneous manifestation secondary to infection in some subcutaneous foci. A 33-year-old patient was admitted to the Clinical Hospital with exudative skin lesions on the back and thorax, initiated 10 months previously, associated with daily fever, and constipation. Spine resonance showed a paravertebral pseudotumoral lesion with T4 and T9 invasion, including vertebral canal and sub-ligament extension. The lesions presented fistulas for paravertebral muscles, lung and skin. Polimerase chain reaction (PCR) proved positive for Mycobacterium tubeculosis in the thorax wound secretion, caracterizing tuberculous spondilodiscitis with scrofuloderma. Treatment was initiated with rifampicin, isoniazid, pyrazinamide and ethambutol with important clinical improvement after the first week. The febrile peaks came to an end and there was improvement in the pattern of the cutaneous lesions. The susceptibility test showed resistance to isoniazid
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Thoracic Injuries
/
Tuberculosis, Cutaneous
/
Discitis
/
Mycobacterium tuberculosis
Type of study:
Risk factors
Limits:
Humans
Language:
English
Journal:
Rev. patol. trop
Journal subject:
Tropical Medicine
/
Pathology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital das Clínicas, UFG/BR
/
Institute of Tropical Pathology and Public Health, Federal University of Goiás (UFG)/BR
/
Institute of Tropical Pathology and Public Health, Federal University of Goiás (UFG/BR
/
Tropical Diseases Hospital Dr Anuar Auad/BR
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