[Autoimmune hypothyroidism with dermopathy and ophthalmopathy [a case report]]

ABSTRACT

Pretibial myxedema is a rare dermatologic disease with unknown pathogenesis, which occurs very rarely, in non-thyrotoxic thyroid diseases. Review of literature, showed only two cases of hypothyroidism with ophthalmopathy and dermopathy. The case was a 48-year-old man presented with preorbital edema, mild proptosis, thyromegaly and pretibial skin lesions. There was no history of hyperthyroidism in the past. Laboratory tests showed primary hypothyroidism with high titers of Anti-TPO antibody and hyperchiosterolemia. CT scan of orbit showed no extraocular muscle involvement. Sodium levothyroxin was prescribed. Sometime later hyperchiosterolemia resolved and patient became euthyroid. Because of limited skin lesions, no dermatologic treatment was prescribed