Influence of supplemental selenium and vitamin E on immunobiological reactivity of sheep vaccinated with chlostridial vaccine

ABSTRACT

Forty ewes were vaccinated with Cl. perfringens vaccine during the last third of gestation period and supplemented according to the divided groups The first group received selenium, the second received vitamin E, the third received both selenium and vitamin E and the fourth group served as control. The injected dose was 5 mg sodium selenite and 400 mg tocopherol. Selenium and /or vitamin E improved the antibody titers for clostridial toxiodes [beta and epsilon] in ewes and their lambs, by their intensification of protein synthesis. Better results were obtained when both selenium and vitamin E used simultaneously with the vaccine