Effect of catharanthus roseus, Don, extracts on trichophyton mentagrophytes

ABSTRACT

The effects of the watery and alcoholic extracts of Catharanthus roseus leaves on Trichophyton mentagrophytes infection of cats and humans was investigated. The watery extract has no clearing therapeutic effect on the infection in both animals and patients. The alcoholic extract of the plant leaves at a concentration of 4% gave a notable effect. It caused complete healing of 83.3% of the affected cats and 77.8% of patients with Tinea pedis due to Trichophyton mentagrophytes infection. The treatment was by local application for four weeks. No side effects were detected during the period of treatment