Fractional flow reserve and appropriateness of angioplasty in moderate coronary stenosis
Journal of Tehran Heart Center [The]. 2007; 2 (3): 151-156
in English
| IMEMR
| ID: emr-100621
ABSTRACT
Percutaneous coronary angioplasty [PTCA] of a coronary stenosis without documented ischemia at noninvasive stress testing is often performed, but its benefit is unproven. Coronary pressure- derived fractional flow reserve [FFR] is an invasive index of stenosis severity defined as the ratio of maximal blood pressure in a stenotic vessel to the normal maximal pressure in the same vessel. FFR is a reliable substitute for noninvasive stress testing and values below 75% identifies stenoses with hemodynamic significance. It is a method that can provide a reliable assessment of coronary stenosis especially in those with intermediate lesions. It can highly impact on decision-making in therapeutic planning and prevent many unnecessary procedures that are routinely done in these cases. In the present study, we report the results of FFR measurements in a series of patients, and this is the first report on the FFR measurement in Iran. The FFR measurement was performed for eleven vessels with intermediate stenosis, and in seven lesions [63.6%] it led to changes in the treatment strategy. On the basis of FFR, percutaneous coronary intervention [PCI] was changed into medical follow-up in five lesions, medical follow-up changed to PCI in one lesion, and coronary artery bypass grafting [CABG] changed to medical follow-up in another
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Angioplasty, Balloon, Coronary
/
Coronary Artery Bypass
/
Coronary Disease
/
Coronary Stenosis
/
Exercise Test
/
Hemodynamics
Limits:
Humans
/
Male
Language:
English
Journal:
J. Tehran Heart Cent.
Year:
2007
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