Paraoxonase inhibition by propranolol
IJPR-Iranian Journal of Pharmaceutical Research. 2004; 3 (3): 155-158
in English
| IMEMR
| ID: emr-102841
ABSTRACT
There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. Lineweaver-Burk and secondary plots were drawn and showed that propranolol is a mixed non-competitive inhibitor of paraoxonase
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Propranolol
/
Adrenergic beta-Antagonists
/
Atherosclerosis
/
Lipids
Language:
English
Journal:
Iran. J. Pharm. Res.
Year:
2004
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