Synthesis of certain 4 [3H] quinazolinone compounds containing imidazolinone and azomethine moieties

ABSTRACT

The synthesis of several 3-[4-arylindine-2-alkyl [aryl] 5[4H] imidazolon-1-yl] phenyl]-2-methyl-7-nitro-4 [3H]-quinazolinones are described. Structured establishment of the new compounds is substantiated by element analysis, IR and h- NMR spectra. Preliminary biological screening of some selected members showed no detectable antimicrobial activity in vitro, chloramphenicol and nystatin were included in the study for sake of comparison