Some immunological abnormalities in bronchiectatic children

ABSTRACT

This study was conducted on - twenty patients with bronchiectasis and 20 apparently healthy children. Their ages ranged from 6-12 years. This article examined the immunoglobulins level [IgG, IgM. IgA] alpha-1 antitrypsin and auto-antibodies on 20 bronchiectatic children as well as 20 control Children The studied group showed a significant [P<0.05] higher mean lgG and IgA as compared to the control group. As regard IgM and alpha-1- antitrypsin there was increased mean levels of IgM and alpha-1- antitrypsin among bronchiectatic children but this was statistically insignificant. Auto-antibodies showed highly significant value [P<0.01] when compared to control. There was a positive significant correlation [P<0.05] between alpha-1 - antitrypsin and IgG while this correlation was insignificant [P>0.05] between alpha-1 -antitlypsin and gM as well as alpha-1 antitrypsin and IgA bronchiectatic children