Efficacy of two plant extracts against vaginal trichomoniasis
Journal of the Egyptian Society of Parasitology. 2009; 39 (1): 47-58
in English
| IMEMR
| ID: emr-105958
ABSTRACT
Trichomoniasis vaginalis is now an important worldwide health problem. Metronidazole has so far been used in treatment, but the metronidazole-resistant strains and unpleasant adverse effects have been developed. Treatment of patients with metronidazole refractory vaginal trichomoniasis constitutes a major therapeutic challenge and treatment options are extremely limited. In the present study, 33 metronidazole-resistant T. vaginalis females were treated with a combined course of metronidazole and tinidazole. Those still resistant to the combined treatment were given Commiphora molmol [Myrrh] as two capsules for six to eight successive days on an empty stomach two hours before breakfast. Also, natural plant extract purified from [Roman] was in-vitro investigated for its efficacy against T. vaginalis on fresh Diamond media. The anti-trichomoniasis vaginalis activity of both P. granatum [in-vitro] and C. molmol [in-vivo] extracts gave promising results:
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Tinidazole
/
Trichomonas Vaginitis
/
Plant Extracts
/
Treatment Outcome
/
Commiphora
/
37052
/
Metronidazole
Limits:
Female
/
Humans
Language:
English
Journal:
J. Egypt. Soc. Parasitol.
Year:
2009
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