Combined general anesthesia and peribulbar block with ropivacaine and colonidine in patients undergoing retinal detachment surgery

ABSTRACT

The aim of this study was to evaluate the effects of peribulbar injection of 1% ropivacaine and hyaluronidase with 0.5 microg/kg clonidine combined with GA on the occurrence of oculocardiac reflex, IOP, surgical bleeding, postoperative pain, and occurrence of postoperative nausea and vomiting [PONV]. We enrolled 60 patients scheduled for primary retinal detachment surgery. They randomly allocated to one of two groups to receive either GA plus PB block by 1% ropivacaine and hyaluronidase 16 lU/mL with clonidine in a dose of 0.5 micro g/kg [PB group, n= 30] or GA alone [control group, n = 30]. In the PB group, the incidence of oculocardiac reflex was decreased; intraocular pressure and surgical bleeding were reduced. Immediate postoperative pain scores were lower, and the time of administration of the first postoperative analgesic was longer. Both the number of patients who required an analgesic supplement and the total amount of additional analgesic requested were smaller in the PB group. The two groups were similar with respect to the incidence of postoperative nausea and vomiting. PB block combined with GA was superior to GA alone for retinal detachment surgery with scleral buckling, resulting in less intraoperative bleeding and less incidence of intraoperative occurrence of oculocardiac reflex and also improving postoperative analgesia