Incidental prostatic carcinoma: incidence and follow-up study

ABSTRACT

The incidence of incidental prostatic carcinoma has been studied in a series of 110 prostatectomy specimens, diagnosed clinically as benign prostatic enlargement without any clinical, laboratory or radiological evidence of malignancy. Age varied from 52-80 years. Pathological examination of serial sections of each specimen revealed two groups, the first group formed of five cases, small in size [less than 3 mm in diameter], localized without any infiltration of prostatic tissue. They were diagnosed as well differentiated adenocarcinoma. The second group formed of four cases, with larger size up to 8 cm in diameter. They were diffuse and infiltrating prostatic tissue. Two cases were diagnosed moderately differentiated adenocarcinoma, and the other two were poorly differentiated. Follow up study was done for three years, the first group showed no evidence of local recurrence or distal spread, one of the moderately differentiated cases showed local recurrence after one year, but the poorly differentiated cases died within six months