Effect of ophthalmic irrigating solutions on biophysical properties of lens, aqueous and vitreous humours

ABSTRACT

In a series of comparative studies to decide which of BSS plus, BSS or Ringer's lactate irrigating solution is mimic as closely as possible to aqueous humor and vitreous body, so as to maintain normal ocular metabolism and integrity of the ocular functions which should be preserved. New Zealand mature rabbits were used to study the effect of mentioned irrigating solutions on the molecular weight distribution and electrophoretic mobilities of lens aqueous and vitreous humors after 72 hours of the eye in vivo irrigation. The presented study showed a significant fluctuations in the molecular weight distribution and electrophoretic mobilities of BSS irrigating solution, while it is nearly the same profile as in the normal control group in case of eyes irrigated with BSS plus and Ringer's lactate solutions. From the results of the presented study and that of previous research of our collegues, it is preferable to use Ringer's lactate solution widely as it is cheaper and safer to the eye than the other maintained studied irrigating solutions