Lipid profile in middle aged psoriatic men

ABSTRACT

Total serum cholesterol, triglycerides and different fractions of lipoproteins [alpha HDL], pre-B [VLDL] and [LDL] were determined in male psoriatics with skin surface area affection less than 50% [n = 20] and in male psoriatics with skin surface affection more than 50% [n = 20] as well as in twenty age-matched healthy males serving as control. Total serum triglycerides and pre-B lipoprotein levels were found to be significantly elevated in both psoriatic groups as compared to healthy control males. While there was a statistically significant decrease in the level of alpha lipoproteins in both psoriatic groups as compared to control group. It can be concluded that at least middle aged men with psoriasis have a tendency to hyperlipoproteinemia which correlates well with the extent of skin involvement. This plasma lipid pattern; hypertriglyceridemia, increased VLDL and low HDL make patients with psoriasis more prone to develop occlusive vascular disease than would be expected in normal population