Kinetics of aminolysis of some antibacterial vinylic ketones II Effect of solvents on aminolysis of trans -3- [p-substituted phenyl] -1- phenyl- prop -2-en -1-one

ABSTRACT

The reactions of a series of trans-3-[p-substituted phenyl]-1-phenyl- prop-2-en-1-ones Ia-e with p-toluidine and p-nitroaniline IIa, b have been studied in benzene, and their reaction rates were measured. In addition, activation parameters delta H* and delta S* were evaluated, and good Hammett correlation with positive P values of 1.2-1.9, were obtained which suggest the anionic character of the transition state