Additivity of the polar substituent effects in kinetics of aminolysis reaction of some trans-3- [p-substituted phenyl] -1-phenyl-prop-2-En-1-ones

ABSTRACT

The reaction kinetics of nucleophilic addition of aromatic amines to trans-3-[P-substituted phenyl]-1-phenyl prop-2-en-1-ones were studied as a function of the structural variation in both reactants. The four-parameter of the equation log kg=log ko + pe sigma + r sigma sigma + were used for dual variation which is characterized by the structural constants sigma and sigma +. This equation indicates that the resonance stabilization of the ground and transition state is the main factor that governs the relative reactivities of the nucleophiles