Reactions of di-and tri-hydric phenolic drugs with trioxalato ferrate [III] reagent and their analysis in aqueous media

ABSTRACT

Simple rapid and reliable spectrophotometric procedures were adopted for microdetermination of catechol, dopamine hydrochloride [drug] and pyrogallol using trioxalatoferrate [III] complex [A] as a coloring reagent via formation of colored mixed ligand chelates with these phenolic drugs. A series of experiments were performed covering a wide range of concentration of the abovementioned drugs in the suitable conditions. The standard deviation was calculated and found to be 0.1 to 1.22. The obtained results indicated the successful application of complex [A] as selective indicator for microdetermination of dopamine in its pharmaceutical ampules and total catecholamines in urine samples of some tumor Egyptian patients