Tissue response to a kaltostat wound dressing in tooth extraction in diabetes

ABSTRACT

The purpose of the present work was to study the effect of kaltostat on the healing process after tooth extraction in guinea pigs with induced diabetes. Nine guinea pigs were used after induction of diabetes by a single subcutaneous injection of a freshly prepared Alloxan mono-hydrate in saline solution. The animals were considered definitely diabetic only when the non-fasting blood sugar level was above 180 mg%. So, it was recommended to use the kaltostat in diabetic patients after teeth extraction in combination with any systemic prophylactic antibiotics to avoid the development of fibrinolytic alveolitis and to accelerate the healing process without expecting any harmful side effects