Toxoplasma lgG and lgM antibodies, a case control study

ABSTRACT

This study includes 62 eases of spontaneous abortions and 75 cross matched non pregnant multiparous women as controls. Micro - ELISA test was done to assess the extent of infection by Toxoplasma IgM and IgM antibodies. Out of 62 aborting women, 26 gave positive antitoxoplasma IgG antibodies [43, 56%] more than 45 Eu/ml and 28 gave positive antitoxoplasma IgM antibodies more than 40 Eu/ml without statistical significant difference. There was a significant difference between aborting women and the controls as regards IgG and IgM antibodies. Regarding antitoxoplasma IgG antibodies, there was a statistical significant difference between those with no previous abortions or 1 - 2 abortions versus those with 3 and more abortions. The infection was more among aborting women in rural than urban area. Also it is evident than risk factors contributing to the tranmission of disease among aborting women indicate unhygienic measures awareness about the mode of transmission of toxoplasma infection. It is recommended that women should be protected from toxoplasma infection and routinely examined for toxoplasma antibodies before marriage or pregnancy