Evaluation of DNA in gingival tissue of patients with early-onset periodontitis

ABSTRACT

A total number of 30 subjects participated in this study, 24 patients with EOP and 6 control subjects. Gingival biopsies were obtained from EOP patients and control group and were prepared for measurement of DNA content and for quantitative assessments of cells in the cell cycle phases. The results showed that no changes were found in DNA content in gingival tissue of EOP patients when compared with control group. Also, a significant difference was observed in cell image analysis of intermitotic phases of cell cycle between PP and RPP when compared with controls in both epithelium and connective tissue cells while no significant difference was observed between JP and PJP when compared with controls