Study of hepatitis E virus infection among children with acute hepatitis in Kaliobiya Governorate

ABSTRACT

This work aimed to study the prevalence of IgG and IgM antibodies to HEV among Egyptian children presenting with acute hepatitis and jaundice [100 patients] by means of a solid phase enzyme immunoassay [EIA] based on two recombinant hepatitis E virus antigens. It was found that the prevalence of anti-HEV IgM and IgG antibodies was 8% and anti-HEV IgG alone was 16% and the total cases of HEV infection was 24%. There was no significant difference with various specific age group, sex, residence and water supply; but there was a significant difference with sewage disposal between groups as regard the causative virus