Biochemical studies on human adenosine deaminase related to neurological function and the effect of blood transfusion and some inhibitors on its activity
Journal of the Egyptian Medical Association [The]. 1988; 71 (5-8): 389-401
in English
| IMEMR
| ID: emr-10880
ABSTRACT
Human erythrocyte adenosine deaminase [adenosine aminohydrolase ADA, EC 3.5.4.4] in normal and some patients suffering from mental retardation was investigated before and after transfusion therapy. We standardized a new and simple spectrophotometric assay of adenosine deaminase based on the continuous monitoring of the reaction products, inosine and ammonia by a NADH-coupled enzyme system. The inhibitory effect of some adenosine analogues on the activity of erythrocyte adenosine deaminase was investigated
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Blood Transfusion
/
Neurophysiology
Language:
English
Journal:
J. Egypt. Med. Assoc.
Year:
1988
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