Palmoplantar psoriasis: treatment with calcipotriol and local UVA radiation compared with local PUVA
Journal of Lasers in Medical Sciences. 2011; 2 (1): 1-5
in English
| IMEMR
| ID: emr-109127
ABSTRACT
Palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. The most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local PUVA. Frequently, it is a recalcitrant disease. We investigated the efficacy and tolerability of the combination of topical calcipotriol with local UVA radiation in comparison with local PUVA therapy. In a total of 43 patients with palmoplantar psoriasis, 33 were given 15 sessions of local UVA radiation and topical calcipotriol and the remainder received 15 sessions of local PUVA [psoralen + UVA radiation]. The statistical analyses of the results showed that the effect and tolerability of both therapeutic modalities are comparable. Combination of topical calcipotriol and local UVA radiation is an optional corticosteroid-free therapeutic modality for palmoplantar psoriasis. It has a comparable effectiveness and tolerability with local PUVA
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
J. Lasers Med. Sci.
Year:
2011
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