[ survey on the potential risks of admixing intramuscular ampoules in Damascus]

ABSTRACT

The aim of the study is the survey intended to assess the awareness of the potential effects of admixing intramuscular ampoules on their bioavailability in Syrian clinics, hospitals and pharmacies. Questionnaires were distributed to the different health settings in Damascus, a response of 62% was obtained. Main findings show that some of the personnel involved in admixing intramuscular ampoules are unaware of any potential risks of admixing intramuscular ampoules. The study came out with recommendations, the most important of which is to avoid any extemporaneous admixtures and to further investigate the suitable formulations of desirable admixtures by professional people, to make sure that there are no risks of precipitation or deactivation due to the change in pH, drug-drug interactions, and dilution