[Effect of infection on serum lipid level, a prospective study in Iran]

ABSTRACT

Serum lipid level may change due to acute febrile illness. This study was designed to evaluate serum lipid level changes in acute infectious diseases and emphasis on importance of serum lipid level measurement in infectious disease. This study also compares diagnostic value of serum lipids and acute phase reactant markers. This study was performed on 100 critically ill patients in 3 tertiary care hospitals in Tehran, Iran. 50 patients with infectious diseases were selected as case group and 50 patients without infectious diseases as control group. Serum level of total cholesterol [TC], high density lipoprotein [HDL], low density lipoprotein [LDL] and triglyceride [TG] were compared in case and control groups. Patients with critical illness and infection had lower level of HDL than patients with critical illness without infection. Mean and standard deviation of FIDL was 40 +/- 19 in case and 53 +/- 14 in control groups. HDL value as a guide to diagnosis infection is equal to erythrocyte sedimentation rate [ESR] and C- reactive protein [CRP]. Serum lipid level change in acute febrile illness. Serum level of high density lipoprotein decreases in infectious diseases and diagnostic value of high density lipoprotein is equal to erythroeyte sedimentation rate [ESR] and C- reactive protein [CRP] in our study