Synthesis and antimicrobial activity study of new-1-carboxamido-3-[-4-naphthyl sulphonamidophenyl]-5-aryl substituted 2-pyrazoline

ABSTRACT

In view of potential biological activity of pyrazoline[1-4] it was considered worth while to synthesize some new-1-carboxamido-3-[-4-naphthyl sulphonamido-phenyl]-5-aryl-substituted-2-pyrazoline by the action of semicarbazidehydro-chloride with 1-[3-naphthyl sulphonamidophenyl]-3-aryl prop-2-ene-1-one [1a-d] in basic medium. The synthesized compounds have been characterized by elemental analysis, I.R. and [1]H-NMR spectra analysis and screened for antimicrobial activity