Your browser doesn't support javascript.
loading
Soluble Fas in pemphigus vulgaris
Archives of Iranian Medicine. 2011; 14 (3): 200-201
in English | IMEMR | ID: emr-110318
ABSTRACT
The Fas/Fas ligand [FasL] system has been recognized as an important pathway for apoptosis induction in cells and tissues. It has recently been shown that skin lesions of pemphigus vulgaris are associated with Fas mediated apoptosis. The aim of this study was to evaluated the level of serum soluble Fas of ten newly diagnosed patients with pemphigus vulgaris. Sera were collected from ten patients with pemphigus vulgaris. Commercial sandwich enzyme-linked immunosorbent assay [ELISA] for quantitative detection of soluble Fas was applied. Patients with mucosal skin involvement had higher median values in contrast to patients with cutaneous involvement. Elevation of soluble Fas in our study may give insights for the pathogenesis of pemphigus vulgaris. Suppression of this underlying mechanism may be an important target for novel therapies and relapse prevention
Subject(s)
Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Enzyme-Linked Immunosorbent Assay / Apoptosis / Fas Ligand Protein / Fas-Associated Death Domain Protein Limits: Female / Humans / Male Language: English Journal: Arch. Iran. Med. Year: 2011

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Enzyme-Linked Immunosorbent Assay / Apoptosis / Fas Ligand Protein / Fas-Associated Death Domain Protein Limits: Female / Humans / Male Language: English Journal: Arch. Iran. Med. Year: 2011