Preparation, characterization, thermal studies, photochemical behaviours and antimicrobial activity of complexes derived from 5-methyl-3-furaldehyde thiosemicarbazone and HG[II] salts of hallo acids

ABSTRACT

Complexes from of 5-methyl-3-furaldehydethiosemicarbazone [5M3HFTSC] and Hg[II] salts derived from inorganic [HCl] and organic hallo acids [CHCl2COOH or CF3COOH] have been prepared. There chemical structures were characterized using elemental analyses, conductivity spectral measurements, thermogravimetric methods and photochemical behaviours. The thermal studies of such complexes using thermogravimetric analysis [TGA], derivatives thermogravimetry [DrTG] from ambient temperature to 750°C showed three decomposition steps. These studies indicated that the thermal decompositions are not simples. The photolysis of the studied compounds has been carried out in the presence of H2O2. It was found that, the photolysis was enhanced in the presence of H2O2 due to the generation of .OH radicals which are very strong oxidizing agent. Biological activity of theses compounds was tested and screened for their in-vitro antibacterial and antifungal activity. The mixed ligand complexes generally are more active than the binary and free thiosemicarbazne ligand