Inhibit free radical-mediated DNA damage by ginkgo biloba extract

ABSTRACT

The presence of plant extract of Ginkgo biloba in the reaction mixture containing calf thymus DNA and free radical generating system protect DNA against oxidative damage to its deoxyribose sugar moiety. The effect was dependent on the concentration of plant extract. These studies suggest that the observed hepatoprotective effect of this plant extract may be due to their ability to suppress the oxidative degradation of DNA in the tissue debris