Use of Al-Sidr honey for treatment of suppurative otitis media, in vivo study

ABSTRACT

Suppurative otitis media is a common disease affecting all ages and both sexes. Development of bacterial resistance is very common making difficulties in management of both acute suppurative otitis media [Ac s o m] and chronic suppurative otitis media [Ch s o m] cases. More recently, interest in honey as a therapeutic agent has undergone a renaissance. Honey is used for management of infected wounds, burns and exhibited excellent results against Gram +ve and Gram-ve organisms in vitro and in some in vivo studies on infected wounds. To compare results of using Al-sidr honey and antibiotics for treatment of acute and chronic suppurative otitis media. Culture and sensitivity of honey, using agar incorporation technique to prepare plates containing serial dilutions of honey to detect MIC for the selected organisms. Preparing honey as ear drops 10% more than MIC. One hundred twenty patients, 60 with [Ac s o m] and 60 with [Ch s o m] divided into 2 groups, Group 1 honey group divided into Group 1A 30 patients with ac s o m [10 with Streptococcus pneumonia, 10 with Haemophilus influenza and 10 with Moraxtila catarrhalis] and Group IB 30 patients with ch s o m [10 with Pseudomonas aeroginosa, 10 iuith KLebsiella and 10 with Proteus] treated by Al-sidr honey local ear drops. Group 2 antibiotic group same distribution as group 1 and treated by antibiotics. There is significant differences between using honey and traditional approach for antibiotic use even after CIS without side effects or complications. We recommend start thinking to use Al-sidr honey as local ear drops for management policies of suppurative otitis media