Comparison of prophylactic use of intrathecal meperidine and intravenous ketamine plus midazolam for preventing of shivering during spinal anesthesia
New Egyptian Journal of Medicine [The]. 2009; 41 (1): 88-94
in English
| IMEMR
| ID: emr-113103
ABSTRACT
Shivering associated with spinal anesthesia is uncomfortable and may interfere with monitoring, we performed this randomized study to compare the efficacy of intrathecal [IT] 0.2 mg/kg meperidine [group M] with that of intravenous [I.V] low dose combination of ketamine 0.25 mg and midazolam 37.5 microg/kg [group KM] in the preventing of shivering caused by spinal anesthesia .This study was carried out on forty patients [ASA I - II]. patients were randomly distributed into two groups 20 patients each submitted to orthopedic surgery were included. Spinal anesthesia was performed in all with bupivacaine and fentanly. During Surgery a Shivering Score was recorded at 5 min intervals. Tympanic and axillary temperature was recoded at 10 min intervals during the perioperative period. After 15 min the incidences of shivering in groups [M] and [K.M] were 25%, 10% respectively. The differences between group KM and group M were statistically significant p=0.026 No patient with shivering Score of >/= 3 was reported in this study. Prophylactic use of ketamine 0.25 mg/kg + midazolam 37.5 microg/kg I.V. was more effective than meperidine 0.2 mg/kg IT in preventing shivering developed during spinal anesthesia
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Shivering
/
Injections, Spinal
/
Comparative Study
/
Injections, Intravenous
/
Ketamine
/
Meperidine
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
New Egypt. J. Med.
Year:
2009
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