comparative study on the effect of fentanyl and d-tubocurarine pretreatments of intra-ocular pressure

ABSTRACT

This work was designed to compare the effect of fentanyl and d-tubocurarine pretreatments on normal intraocular pressure [lOP] during general anaesthesia. One hundred patients of both sexes and middle age submitted to elective ophthalmic surgery were the subject of this comparative study.These patients were divided into two equal groups. All patients were premedicated by 0.01 mg/kg atropine sulphate I.M. Two minutes before induction 2 ug/kg fentanyl and 0.05 mg/kg d-tubocurarine were I.V. injected in the first and the second group respectively. Anaesthesia was induced by thiopentone Na followed by suxamethonium [1 mg/kg] and endotracheal intubation and was maintained under fluothane and oxygen. From this study, it was found that fentanyl pretreatment was superior to d-tubocurarine as pretreatment of control lOP especially during suxamethonium administration and endotracheal intuabation