HBsAg and anti-HBsAg detection: results of comparative testing in HBV endemic area
Saudi Medical Journal. 1987; 8 (5): 510-3
in English
| IMEMR
| ID: emr-114529
ABSTRACT
When 2139 saudi blood samples were screened for hepatitis B surface antigen [HBsAg] by reverse passive haemagglutination [RHPA] the prevalence rate was 4.3% 54 samples were inconclusive for the presence of HBsAg and 31 samples were HBsAg positive only at a serum dilution of 140. These inconclusive low positive samples along with 1000 randomly chosen HBsAg negative [RPHA] samples were retested for HBsAg by radioimmunoassay [RIA] and enzyme immunoassay [EIA]. The samples which were HBsAg negative [RIA] were also tested for antibody to HBsAg [anti-HBs] by passive haemagglutination [PHA], RIA and EIA Comparative testing showed RPHA and PHA to be the last sensitive for the detection of HBsAg and anti-HBs respectively while RIA was the most sensitive followed closely by EIA in the detection of both the antigen and the antibody
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Mass Screening
/
Hepatitis B Antibodies
/
Hepatitis B Surface Antigens
Type of study:
Screening study
Language:
English
Journal:
Saudi Med. J.
Year:
1987
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