new anti-epileptic drugs: a clinical profile

ABSTRACT

Over the past few years, a number of new anti-epileptic drugs have been introduced including gabapentin, lamotrigine, vigabatrin, topiramate, felbamate and tiagabine. Several clinical studies showed efficacy of these anti-epileptic drugs on various types of seizures. However, the pharmacologic and clinical properties of these drugs remain to be fully defined. In this review, the pharmacokinetics, indications, and side-effects of the new anti-epileptic drugs are summarized