Oral bacteriological findings testing the sensitivity and resistance of bacteria to antimicrobial agents

ABSTRACT

Micro biological investigations were carried out on oral infective diseases, reporting to Department of Dental Public Health Research Unit, College of Community Medicine, Lahore. The study is based on total sample of 650 cases. The range of the age was 20 to 40 years belonging to well to do socio-economic class study included 344 male, 316 female from November 1974 to November 1979. Bacteriologically positive cases of periodontal disease had the following distribution of the micro-organisms. Pus cells were found only in 38% of cases, gram positive cocci 95, 44.61% gram negative cocci in 2.61% fusiform bacilli and spirochaetes were detected in 30.30% cases respectively. Culture reports revealed Staphylococcus pyogenes, 55.00% non-haemolytic streptococci, 17.68%, haemolyticus streptococci 7.38%, alpha haemolyticus streptococci 4.76%, beta haemolytic streptococci 3.07%; streptococcus viridans, 1.23%; streptococcus pneumoniaie, 0.30%; Escherichia coli, 9.69%; pseudomonas aeruginosa, 0.15% Klebsiella pneumoniae 0.46%; proteus vulgaris, 0.61% and haemophilus influenza, 0.61%. The sensitivity and resistance reports have shown very interesting results. Pencillin is being observed as the most resistant drug to oral bacteria, whereas chloramphenicol has proved to be excellent sensitive for positive cases. The other antibiotics have also indicated their trend of resistance. The study has been further split up to each bacteria and its sensitivity and resistance to each antibiotic. Similar resistance has been observed in tetracycline group. The utility of this study is of great importance for those who seek help of anti-biotics in their practice