Intracavernous injections of papaverine and phentolamine for treatment of impotence

ABSTRACT

Intracavernous injections of papaverine hydrochloride with phentolamine mesylate rapidly produce transitory penile tumescence, which can be followed by erection and coitus provided there is sexual stimulation. A total of 45 men with impotence underwent trial of intracavernous drug induced erection with a mixture of papaverine and phentolamine. Full tumescence and maximum rigidity'occurred in 38 patients. Good results were seen in patients with impotence of neurogenic origin due to diabetes mellitus