Association of congenital anomalies and malignancies of head and neck

ABSTRACT

Ninteen cases of congenital anomalies in 506 cases of head and neck malignancies have been encountered in comparison to 3 cases of congenital anomalies in 506 controls. These anamolies are hereditary and some of them are associated with chromosomal abnormalities. The possible explanation of this association between congenital anomalies and malignancies might be genetic factors or abnormal genes, which are responsible for abnormal response manifesting in the form of cancer in presence of predisposing factor