Infection prophylaxis in the myelosuppresed patient with cancer

ABSTRACT

The present prospective study included 29 patients attending the Paediatric Unit of Kasr El-Aini Center of Radiation Oncology and Nuclear Medicine. Eligible patients were randomly allocated to receive or not to receive oral prophylactic antibiotics as well as miconazole [2%] oral gel. Incidence of infection was higher among the control group [77.8%] than the antibiotic group [61%]. However, the difference was not statistically significant. On the other hand, more patients among the control group [86%] significantly developed oral moniliasis than those among the antibiotic group [55.5%] [P = 0.001]