Mesenchymal stem cell; biology, application and its role in regenerative medicine
Scientific Journal of Iranian Blood Transfusion Organization Research Center [The]. 2012; 8 (4): 304-320
in Persian
| IMEMR
| ID: emr-118292
ABSTRACT
Mesenchymal stem cells have extensive potential to proliferate and differentiate into different cell lineages. Their differentiation capability in vivo and in vitro makes them ideal tools for tissue engineering and regenerative medicine. In the present study more than 100 recent published articles which are about isolation, culture and differentiation of MSCs were reviewed for application of MSC in regenerative medicine and tissue engineering. Clinical applications of MSCs seem to be in two distinctive lines bio-scaffold design without immunological responses as well as multipotent stem cell without clinical obstacles. MSCs due to their capacity of self-renewability, multilineage differentiation and immune modulatory effects are of great therapeutic potential for cell and gene therapy of congenital and degenerative disorders
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Cell Differentiation
/
Tissue Engineering
/
Mesenchymal Stem Cell Transplantation
Limits:
Humans
Language:
Persian
Journal:
Sci. J. Iran. Blood Transfus. Organ. Res. Cent.
Year:
2012
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