effect of photodynamic therapy in the management of polypoidal choroidal vasculopathy in a 28-year-old

ABSTRACT

To report on the occurrence of exudative macular polypoidal choroidal vasculopathy in a young healthy patient, and the outcome of photodynamic therapy using vertoporphin. A twenty eight year old female patient with 6/6 vision for distance in both her eyes, presented with reduction in near vision in her left eye. Fundus evaluation supported by evidence provided by optical coherence tomography and fluorescein angiography revealed hemorrhagic retinal pigment epithelial detachment involving the macular area. Polypoidal choroidal vessles located supero temporal to the fovea were detected as causing the subfoveal bleeding on indocyanine green angiography. She was treated with photodynamic therapy using vertoporphin. A reduction in the hypofluorescent area involving the foveal area was noted on fundus fluorescein angiogram and indocyanine green angiogram. Clinically, there was a small pinkish swelling infero nasal to fovea in the left eye. Near Vision showed no improvement. However, central scotoma was replaced by metamorphosia. Optical coherence tomography revealed normal macular area. Polypoidal choroidal vasculopathy as a cause of macular disease in young individuals is rare and to our knowledge has not been reported so far