Noonan syndrome with features of neurofibromatosis type 1: a case report

ABSTRACT

To present a child who developed bilateral Lisch nodules 3 years after he had been diagnosed to have Noonan syndrome. Patient evaluation included complete general and ophthalmic examination, and imaging studies. Bilateral Lisch nodules raised the possibility of neurofibromatosis-Noonan syndrome in an 8-year-old Saudi boy, diagnosed previously to have Noonan syndrome. Signs of neurofibromatosis may appear years after the diagnosis of Noonan syndrome. This mandates periodic ophthalmic evaluation as the ophthalmologist may find the first clue for diagnosing neurofibromatosis-Noonan syndrome