[Abdominal desmoid tumor pathologic and therapeutic concepts]
Tunisie Medicale [La]. 2008; 86 (10): 916-920
in French
| IMEMR
| ID: emr-119747
ABSTRACT
Abdominal desmoid tumors arise in young adults between 20 and 40 years. They are character/i2ed by a local recurrence in 20 to 30% of eases. Review the clinical and pathologic features of this entity, look for the expression of immunohistochemical markers [actine, desmine, CD34, vimentin] and also to estimate the expression of two potential targets therapy; the hormonal receptors and the CD117. From 1990 to 2004, three cases of abdominal desmoid tumors were diagnosed in the Pathologic laboratory of the Charles Nicole Hospital of Tunis. The study concerned three women 62, 35 and 30 year-old. All the patients were operated and the site of tumours varied to 5 to 7cm. The CD117 and the hormonal receptors were negative in every case. None of the patients presented local recurrence. Abdominal desmoid tumors are locally aggressive but never give metastasis. The negativity of these lesions to the CD117 and in the hormonal receptors does not imply resistance in the hormonal treatment by anti-estrogens
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Immunohistochemistry
/
Magnetic Resonance Imaging
/
Retrospective Studies
/
Fibromatosis, Aggressive
/
Fibromatosis, Abdominal
/
Proto-Oncogene Proteins c-kit
/
Abdominal Neoplasms
Type of study:
Case report
Limits:
Female
/
Humans
Language:
French
Journal:
Tunisie Med.
Year:
2008
Similar
MEDLINE
...
LILACS
LIS