Effect of aspirin on nutritional parameters, plasma proteins and blood haemoglobin in growing rats

ABSTRACT

The effect of low and high doses of aspirin [50 and 150 mg/kg rat body weight] on protein efficiency ratio, blood hemoglobin, percentage hematocrit and plasma proteins were studied in growing rats fed balanced diet. Results showed that protein efficiency ratio of rats given the high dose was significantly decreased. Blood hemoglobin increased significantly when aspirin was given. Hematocrit was affected significantly by aspirin treatment. Plasma total protein and globulin increased significantly. Albumin/globulin ratio decreased significantly on administration of both aspirin doses