Effect of a newly developed hematoporphyrin derivative preparation on oral flora during orthodontic treatment

ABSTRACT

This study was designed to assess the effect of topical porphyrin application on some bacterial and fungal species of oral flora after using orthodontic treatment [ODT] which indicated to correct abnormalities of the teeth of patient. A novel porphyrin derivative was used. It was concluded that, all Gram-negative strains appeared to be resistant, except neisseria. Gram-positive strains were significantly inhibited due to porphyrin application. Oral fungus as C and ida albicans were significantly inhibited after porphyrin application