Effect of amitriptyline on blood glycose, insulin, lipids, thyroid function, electrolytes and some brain amino acids in rabbits
Bulletin of Alexandria Faculty of Medicine. 1986; 22 (1): 131-7
in English
| IMEMR
| ID: emr-120137
ABSTRACT
The intraperitoneal administration of amitriptyline [10 mg/kg body weight for 14 days] resulted in a significant decrease in blood glucose, significant increase in the blood insulin level, significant decrease in the levels of free fatty acids [FFA], triglycerides and total cholesterol. It also produced a significant decrease in both sodium and potassium levels and an increase in brain GABA level. However, T3, T4, TSH and brain L-glutamic acid showed no change. The probable significance of the findings is discussed
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Amitriptyline
/
Animals, Laboratory
Language:
English
Journal:
Bull. Alex. Fac. Med.
Year:
1986
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