Therapeutic effects of tinidazole in periodontal disease

ABSTRACT

Eight patients were participated in this study. Every patient received scaling for one side and the other side left without scaling. Bacterial samples were obtained from both sides before tinidazole therapy [at zero time] and at 2 and 4 weeks after tinidazole therapy. Dark field microscopy was used for bacterial identification and counting. There was a reduction in the total cell count. The counts of spirochetes, rods [motile and non-motile] showed decrease than at the initial counts. The cocci showed a concomitant increase in week 2 and 4 than at week 0. Microbiologically, tinidazole therapy can affect the subgingival microflora quantitatively and qualitatively