Study of glyco protein in gallbladder bile of patients with schistosomal hepatic fibrosis

ABSTRACT

This study was carried out on 30 patients classified into two groups. Group I included 20 patients with schistosomal hepatic fibrosis [12 were non bleeders and 8 were bleeders]. Group II included 10 non schistosomal patients as controls. The aim was the study of changes in the amount of glycoprotein in gall bladder bile in patients with schistosomal hepatic fibrosis and its possible role in lithogenesis of bile. The study revealed a significant increase of gall bladder bile glycoprotein in schistosomal patients, which is a potent nucleating factor for gallstone formation