Studies on blood lipids in thyroid dysfunction

ABSTRACT

Thyroid hormones appear to stimulate virtually all aspects of lipid metabolism including synthesis, mobilization and degradation. The aim of this work to identify and study the changes in blood lipids in patients with disturbed thyroid function. The present study revealed that the serum levels of total lipids, cholesterol, beta and pre-beta lipoproteins were significantly increased in hypothyroid patients, while they were significantly decreased in hyperthyroid patients as compared to control levels. These differences between the hypothyroid and hyperthyroid patients were significant. Alpha lipoprotein [high density lipoprotein] level showed significant decrease in both hypo and hyperthyroid patients as compared to control level, meanwhile the level of hypothyroid patients was insignificantly higher than that of hyperthyroid patients