Low molecular weight heparin versus low-dose heparin in thromboprophylaxis after major abdominal surgery

ABSTRACT

One hundred twenty patients undergoing elective major abdominal surgery were divided into 3 equal groups Group A [LMWH], group B [low-dose heparin] and group C [placebo, control group]. The results showed that both LMWH and low-dose heparin are equally effective in lowering the incidence of postoperative deep vein thrombosis [one case in each group, while four cases developed deep vein thrombosis in the control group]. The bleeding complications were nearly the same in the first two groups and exceeded those reported in the control group. LMWH as it has the same efficacy and side effects of low-dose heparin is a practically alternative way of thromboprophylaxis in patients undergoing elective major abdominal surgery because of the once-daily regimen with better patient acceptance