Interleukin-1 production by monocytes from patients anaesthetized with halothane and isoflurane

ABSTRACT

Twenty female patients formed the population of this study. They were divided into two groups according to the anesthetic agent used for the maintenance of anesthesia. Group I was the halothane group and group II was the Isoflurane group. The aim of this study was to compare the effect of both anesthetics on the liberation of IL-1 from monocytes. The results showed that there were insignificant changes between the two groups in the spontaneous release of IL-1 either immediately or 24 hours postoperatively. But there was a significant difference between the two groups both after activation of monocytes and spontaneous index in the immediate postoperative period. After 24 hours, there was insignificant difference after activation and the stimulation index