Study of plasma d-dimer in coronary heart disease

ABSTRACT

Thirty patients were included in this study. They were divided into three groups. Group I included 10 patients with stable angina. Group II included 10 patients with unstable angina [UA] and group III included 10 patients with acute myocardial infarction [AMI] together with 10 control subjects. They were studied by measuring D-dimer, fibrinogen level, fibrinogen degradation products, euglobulin clot lysis time and plasminogen level. Fibrinogen was significantly higher in UA. D-dimer was obviously significant in 70% of the AMI and 80% in unstable angina. FDPs were increased, ELT showed significant prolongation and lower level of plasminogen in AMI. D-dimer test can be considered as a simple easy rapid side test for detection of thrombotic or may be prethrombotic conditions